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diff --git a/academic/bowtie/README b/academic/bowtie/README new file mode 100644 index 000000000000..949e67e5f8a1 --- /dev/null +++ b/academic/bowtie/README @@ -0,0 +1,17 @@ +Bowtie is an ultrafast, memory-efficient short read aligner geared +toward quickly aligning large sets of short DNA sequences (reads) to +large genomes. It aligns 35-base-pair reads to the human genome at a +rate of 25 million reads per hour on a typical workstation. Bowtie +indexes the genome with a Burrows-Wheeler index to keep its memory +footprint small: for the human genome, the index is typically about +2.2GB (for unpaired alignment) or 2.9GB (for paired-end or colorspace +alignment). Multiple processors can be used simultaneously to achieve +greater alignment speed. Bowtie can also output alignments in the +standard SAM format, allowing Bowtie to interoperate with other tools +supporting SAM, including the SAMtools consensus, SNP, and indel +callers. + +If you use Bowtie for your published research, please cite: +Langmead B, Trapnell C, Pop M, Salzberg SL. +Ultrafast and memory-efficient alignment of short DNA sequences to +the human genome. Genome Biol 10:R25. |