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author | Petar Petrov <slackalaxy@gmail.com> | 2017-05-02 23:14:12 +0700 |
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committer | Willy Sudiarto Raharjo <willysr@slackbuilds.org> | 2017-05-02 23:14:12 +0700 |
commit | 1d699e8527bc9d1429493534755fba5d6cfd0333 (patch) | |
tree | 4f20fcf514c3913f7d6f00bfe1cf29a700b9ab32 /academic/prank-msa/README | |
parent | 3057c44df8997b0dbf07b7a5e5ed1cf1722d0e03 (diff) |
academic/prank-msa: Added (probabilistic alignment program).
Signed-off-by: Willy Sudiarto Raharjo <willysr@slackbuilds.org>
Diffstat (limited to 'academic/prank-msa/README')
-rw-r--r-- | academic/prank-msa/README | 32 |
1 files changed, 32 insertions, 0 deletions
diff --git a/academic/prank-msa/README b/academic/prank-msa/README new file mode 100644 index 000000000000..4bc1a9f838f1 --- /dev/null +++ b/academic/prank-msa/README @@ -0,0 +1,32 @@ +PRANK: Probabilistic Alignment Kit + +PRANK is a probabilistic multiple alignment program for DNA, codon and +amino-acid sequences. It is based on a novel algorithm that treats +insertions correctly and avoids over-estimation of the number of +deletion events. + +In addition, PRANK borrows ideas from maximum likelihood (ML) methods +used in phylogenetics and correctly takes into account the evolutionary +distances between sequences. + +Lastly, PRANK allows for defining a potential structure for sequences to +be aligned and then, simultaneously with the alignment, predicts the +locations of structural units in the sequences. + +NOTE! +The dependencies listed in the REQUIRED field are not needed for +building PRANK. They are, however, highly recommended for the complete +functionality of the program: + +1) Progressive alignment requires a guide tree. If no tree is provided, +PRANK constructs one by calling MAFFT to make a quick alignment and +infers an NJ tree from the evolutionary distances based on that. + +2) The standard PRANK algorithm is based on an exhaustive search of the +best pairwise solution. PRANK uses Exonerate to anchor the pairwise +alignments and thus speed up the process. + +3) To improve the ancestral reconstruction, PRANK uses BppAncestor from +the BppSuite. + +NOTE 2: This will not build on a 32bit system. |