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authorPetar Petrov <slackalaxy@gmail.com>2018-01-12 22:52:20 +0000
committerWilly Sudiarto Raharjo <willysr@slackbuilds.org>2018-01-13 07:13:05 +0700
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treed916bb2907a77e7f1be38d80a67729c662155408 /academic/RepeatMasker/README
parent7e06cba42fde15af4055d31241cd224ac23ed303 (diff)
academic/RepeatMasker: Added (Screen DNA sequence).
Signed-off-by: David Spencer <idlemoor@slackbuilds.org>
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+RepeatMasker is a program that screens DNA sequences for interspersed
+repeats and low complexity DNA sequences. The output of the program is a
+detailed annotation of the repeats that are present in the query
+sequence as well as a modified version of the query sequence in which
+all the annotated repeats have been masked (default: replaced by Ns).
+
+Currently over 56% of human genomic sequence is identified and masked by
+the program. Sequence comparisons in RepeatMasker are performed by one
+of several popular search engines including:
+
+- nhmmer (part of 'HMMER', available on SBo)
+- Cross_Match. Due to licensing, you should obtain this yourself:
+ http://www.phrap.org
+- ABBlast/WUBlast. Due to licensing, you should obtain this yourself:
+ https://blast.advbiocomp.com/licensing/
+- RMBlast (found as 'ncbi-rmblastn' on SBo)
+
+RepeatMasker makes use of curated libraries of repeats and currently
+supports Dfam (profile HMM library derived from Repbase sequences) and
+Repbase, a service of the Genetic Information Research Institute.
+
+WARNING!
+Due to the bundled databases, the installed size of this is 1.8 GiB!
+
+NOTE!
+The package is installed in /opt. After install go fo /opt/RepeatMasker
+and run the RepeatMasker Configuration Program:
+
+# perl ./configure
+
+See README.SLACKWARE for details.