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author | Petar Petrov <slackalaxy@gmail.com> | 2017-02-04 16:40:59 +0000 |
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committer | Willy Sudiarto Raharjo <willysr@slackbuilds.org> | 2017-02-11 07:24:07 +0700 |
commit | 80d665841bf9045fa91a309ba8cd6cecfc42335d (patch) | |
tree | 9fe086d0dcee30f9986daf1d9ca4ec49b1eebf3d /academic/CAPS_coevolution/README | |
parent | 1852c5a4c13f778f2958fdb83945ce7e068196b8 (diff) |
academic/CAPS_coevolution: Added (Coevolution Analysis).
Signed-off-by: David Spencer <idlemoor@slackbuilds.org>
Diffstat (limited to 'academic/CAPS_coevolution/README')
-rw-r--r-- | academic/CAPS_coevolution/README | 25 |
1 files changed, 25 insertions, 0 deletions
diff --git a/academic/CAPS_coevolution/README b/academic/CAPS_coevolution/README new file mode 100644 index 0000000000000..b0d477c7a2183 --- /dev/null +++ b/academic/CAPS_coevolution/README @@ -0,0 +1,25 @@ +CAPS: Coevolution Analysis using Protein Sequences + +CAPS is aimed at measuring the coevolution between amino acid sites +belonging to the same protein (intra-molecular coevolution) or to two +functionally or physically interacting proteins (inter-molecular +coevolution). The Software implements an improved method to detect +intra-molecular coevolution as published in Genetics (Fares and Travers, +2006) and also inter-protein coevolution analysis. The improved scoring +of amino acid sites is obtained by maximum likelihood ancestral state +reconstruction along with simulations to assess significance. + +In addition, a test which assesses whether two proteins are interacting +is implemented. + +NOTE: +The script just repackages the binaries provided from upstream. + +CITING: +CAPS: coevolution analysis using protein sequences. Fares MA, McNally D. +Bioinformatics. 2006 Nov 15;22(22):2821-2. PMID: 17005535 + +The mathematical model has been described separately: +A novel method for detecting intramolecular coevolution: adding a +further dimension to selective constraints analyses. Fares MA, Travers +SA. Genetics. 2006 May;173(1):9-23. PMID: 16547113 |