diff --git a/src/makefile.osx b/src/makefile.osx
index bef0ef3..07ef8d3 100644
--- a/src/makefile.osx
+++ b/src/makefile.osx
@@ -7,17 +7,21 @@
 # Originally by Laszlo Hanyecz (solar@heliacal.net)
 
 CXX=llvm-g++
-DEPSDIR=/opt/local
+DEPSDIR=/usr/local
+DB4DIR=/usr/local/opt/berkeley-db4
+OPENSSLDIR=/usr/local/opt/openssl
 
 INCLUDEPATHS= \
  -I"$(CURDIR)" \
- -I"$(CURDIR)"/obj \
+ -I"$(CURDIR)/obj" \
  -I"$(DEPSDIR)/include" \
- -I"$(DEPSDIR)/include/db48"
+ -I"$(DB4DIR)/include" \
+ -I"$(OPENSSLDIR)/include"
 
 LIBPATHS= \
  -L"$(DEPSDIR)/lib" \
- -L"$(DEPSDIR)/lib/db48"
+ -L"$(DB4DIR)/lib" \
+ -L"$(OPENSSLDIR)/lib"
 
 USE_UPNP:=1
 USE_IPV6:=1
@@ -31,14 +35,14 @@ ifdef STATIC
 TESTLIBS += \
  $(DEPSDIR)/lib/libboost_unit_test_framework-mt.a
 LIBS += \
- $(DEPSDIR)/lib/db48/libdb_cxx-4.8.a \
+ $(DB4DIR)/lib/libdb_cxx-4.8.a \
  $(DEPSDIR)/lib/libboost_system-mt.a \
  $(DEPSDIR)/lib/libboost_filesystem-mt.a \
  $(DEPSDIR)/lib/libboost_program_options-mt.a \
  $(DEPSDIR)/lib/libboost_thread-mt.a \
  $(DEPSDIR)/lib/libboost_chrono-mt.a \
- $(DEPSDIR)/lib/libssl.a \
- $(DEPSDIR)/lib/libcrypto.a \
+ $(OPENSSLDIR)/lib/libssl.a \
+ $(OPENSSLDIR)/lib/libcrypto.a \
  -lz
 else
 TESTLIBS += \